THOC1

Also known as HPR1, P84, P84N5, THO complex 1

THO complex subunit 1 is a protein that in humans is encoded by the THOC1 gene.

Gene data

THOC1

Name: THO complex subunit 1
Type: protein-coding
Position: 214,515–268,053 (−)
Aliases: DFNA86, HPR1, P84, P84N5
Ensembl: ENSG00000079134
RefSeq RNA: NM_005131.3, XM_011525772.4, XM_011525774.2, XM_017026104.2, XM_047437972.1
RefSeq protein: NP_005122.2, XP_011524074.1, XP_011524076.1, XP_016881593.1, XP_047293928.1

HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 142560).[supplied by OMIM, Nov 2010]

Gene Ontology

Biological process

mRNA export from nucleus mRNA export from nucleus mRNA export from nucleus signal transduction

Molecular function

protein binding identical protein binding

Cellular component

transcription export complex THO complex THO complex part of transcription export complex THO complex part of transcription export complex chromosome, telomeric region nucleus nucleus nucleoplasm

Pathways

RNA transport - Homo sapiens (human)Spliceosome - Homo sapiens (human)Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing Transport of Mature Transcript to Cytoplasm Processing of Capped Intron-Containing Pre-mRNA Metabolism of RNA

via MyGene.info

Gene · Ensembl

THO complex subunit 1

Symbol: THOC1
Biotype: Protein coding
Organism: Homo sapiens
Location: 18:214,249-268,065
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein THOC1 PDB 1wxp.png

Show 5 more facts

HomoloGene ID: 38012
exact match: identifiers.org/ncbigene/9984
genomic end: 268050
genomic start: 214520
cytogenetic location: 18p11.32

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THO complex subunit 1 is a protein that in humans is encoded by the THOC1 gene.

HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 606390).[supplied by OMIM]