THOC2
Sign in to saveAlso known as THO2, CXorf3, dJ506G2.1, hTREX120, MRX12, MRX35, THO complex 2
THO complex subunit 2 is a protein that in humans is encoded by the THOC2 gene.
Gene data
THOC2- Name
- THO complex subunit 2
- Type
- protein-coding
- Chromosome
- X
- Position
- 123,600,561–123,733,061 (−)
- Aliases
- AMC7, CXorf3, MRX12, MRX35, THO2, XLID12, dJ506G2.1, hTREX120
- Ensembl
- ENSG00000125676
- RefSeq RNA
- NM_001081550.2, NM_001441235.1, NM_001441236.1, NM_020449.2, XM_017029679.2
- RefSeq protein
- NP_001075019.1, NP_001428164.1, NP_001428165.1, XP_016885168.1, XP_047298219.1
The TREX multiprotein complex binds specifically to spliced mRNAs to facilitate mRNA export. The protein encoded by this gene is a member of the THO complex, a subset of the TREX complex. The encoded protein interacts with the THOC1 protein.[provided by RefSeq, Jun 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
THO complex subunit 2
- Symbol
- THOC2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:123,600,561-123,733,061
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Structure of an endogenous human TREX complex bound to mRNA 7ZNK THOC2.png
Show 7 more facts
- HomoloGene ID
- 69669
- exact match
- identifiers.org/ncbigene/57187
- found in taxon
- Homo sapiens
- chromosome
- human X chromosome
- genomic end
- 122866906
- genomic start
- 122734412
- cytogenetic location
- Xq25
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
THO complex subunit 2 is a protein that in humans is encoded by the THOC2 gene.
THO2 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), HPR1 (MIM 606930), ALY (MIM 604171), and UAP56 (MIM 606390).[supplied by OMIM]
Excerpted from Wikipedia’s “THOC2” article, available under the CC BY-SA 4.0 licence.