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tiopronin

Structure via PubChem · Public domain (PubChem)

EntityQ414456· pop 10· linked from 56 articles

Also known as alpha-mercaptopropionylglycine, alpha-MPG, Tiopronine, α-MPG

Tiopronin, sold under the brand name Thiola, is a medication used to control the rate of cystine precipitation and excretion in the disease cystinuria.

Key facts

Drug.tradename
Thiola
Drug.DailyMedID
Tiopronin
Drug.DrugBank
DB06823
Drug.ChEBI
32229

via Wikipedia infobox

Chemical data

Formula
C5H9NO3S
Molecular weight
163.2 g/mol
IUPAC name
2-(2-sulfanylpropanoylamino)acetic acid
SMILES
CC(C(=O)NCC(=O)O)S
InChIKey
YTGJWQPHMWSCST-UHFFFAOYSA-N
XLogP
-0.1
Polar surface area
67.4 Ų
H-bond donors
3
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Approved
Molecule type
Small molecule
First approval
1988
Admin. routes
oral
Indications
subarachnoid hemorrhage, drug-induced hepatitis, cystinuria

via ChEMBL · EBI

Wikidata facts

Mass
163.030314
Show 2 more facts
canonical SMILES
CC(C(=O)NCC(=O)O)S
chemical formula
C₅H₉NO₃S
Sources (3)

via Wikidata · CC0

~2 min read

Encyclopedic overview

7 sections
Contents
  • Medical uses
  • Side effects
  • Pharmacology
  • Mechanism of action
  • Society and culture
  • Research
  • References

Tiopronin, sold under the brand name Thiola, is a medication used to control the rate of cystine precipitation and excretion in the disease cystinuria.

It is available as a generic medication.

Excerpted from Wikipedia’s “tiopronin” article, available under the CC BY-SA 4.0 licence.