TNS1
Sign in to saveAlso known as MST091, MST122, MST127, MSTP122, MSTP127, MXRA6, PPP1R155, TNS
Tensin-1 is a protein that in humans is encoded by the TNS1 gene.
Gene data
TNS1- Name
- tensin 1
- Type
- protein-coding
- Aliases
- MST091, MST122, MST127, MSTP091, MSTP122, MSTP127, MXRA6, PPP1R155, TNS
The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015].
via MyGene.info
Gene · Ensembl
tensin 1
- Symbol
- TNS1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:217,799,588-218,033,982
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Tensin-1 is a protein that in humans is encoded by the TNS1 gene.
The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. A second transcript from this gene has been described, but its full length nature has not been determined.
Excerpted from Wikipedia’s “TNS1” article, available under the CC BY-SA 4.0 licence.