TOM1L2
Sign in to saveAlso known as target of myb1 like 2 membrane trafficking protein
TOM1-like protein 2 is a protein that in humans is encoded by the TOM1L2 gene.
Gene data
TOM1L2- Name
- target of myb1 like 2 membrane trafficking protein
- Type
- protein-coding
- Position
- 17,843,507–17,972,470 (−)
- Ensembl
- ENSG00000175662
- RefSeq RNA
- NM_001033551.3, NM_001082968.2, NM_001288786.2, NM_001288787.2, NM_001288788.2
- RefSeq protein
- NP_001028723.1, NP_001076437.1, NP_001275715.1, NP_001275716.1, NP_001275717.1
This gene belongs to a small gene family whose members have an N-terminal VHS domain followed by a GAT domain; domains which typically participate in vesicular trafficking. The canonical protein encoded by this gene also has a C-terminal clathrin binding motif. This protein has been shown to interact with Tollip, clathrin and ubiquitin and is thought to play a role in endosomal sorting. This gene resides in the 3.7 Mb deletion of chromosome region 17p11.2 that is associated with Smith-Magenis syndrome. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Apr 2017].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
target of myb1 like 2 membrane trafficking protein
- Symbol
- TOM1L2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:17,843,507-17,972,470
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- Further reading
TOM1-like protein 2 is a protein that in humans is encoded by the TOM1L2 gene.
==See also== TOM1, target of Myb1 membrane trafficking protein TOM1L1
Excerpted from Wikipedia’s “TOM1L2” article, available under the CC BY-SA 4.0 licence.