TONSL
Sign in to saveAlso known as IKBR, NFKBIL2, tonsoku-like, DNA repair protein, tonsoku like, DNA repair protein, SEMDSP
Tonsoku-like, DNA repair protein is a protein that in humans is encoded by the TONSL gene.
Gene data
TONSL- Name
- tonsoku like, DNA repair protein
- Type
- protein-coding
- Aliases
- IKBR, NFKBIL2, SEMDSP
The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
tonsoku like, DNA repair protein
- Symbol
- TONSL
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:144,428,763-144,444,488
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 22754
- exact match
- identifiers.org/ncbigene/4796
- genomic start
- 145654165
- genomic end
- 144444440
- cytogenetic location
- 8q24.3
Sources (6)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Function
- References
- Further reading
Tonsoku-like, DNA repair protein is a protein that in humans is encoded by the TONSL gene.
== Function ==