TSC22D1
Sign in to saveAlso known as Ptg-2, TGFB1I4, TSC22, TSC22 domain family member 1
TSC22 domain family protein 1 is a protein that in humans is encoded by the TSC22D1 gene.
Gene data
TSC22D1- Name
- TSC22 domain family member 1
- Type
- protein-coding
- Aliases
- HUCEP-2, Ptg-2, TGFB1I4, TSC22
This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011].
via MyGene.info
Gene · Ensembl
TSC22 domain family member 1
- Symbol
- TSC22D1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 13:44,432,143-44,577,433
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 7573
- exact match
- identifiers.org/ncbigene/8848
- genomic end
- 45151283
- genomic start
- 45007655
- cytogenetic location
- 13q14.11
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- References
- Further reading
- External links
TSC22 domain family protein 1 is a protein that in humans is encoded by the TSC22D1 gene.
TSC22 encodes a transcription factor and belongs to the large family of early response genes.