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GeneQ18032950· pop 5· linked from 3 articles

TTF2

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Also known as HuF2, ZGRF6, transcription termination factor, RNA polymerase II, transcription termination factor 2, F2

Transcription termination factor 2 is a protein that in humans is encoded by the TTF2 gene.

Gene data

TTF2
Name
transcription termination factor 2
Type
protein-coding
Position
117,060,285–117,107,453 (+)
Aliases
HuF2, ZGRF6
Ensembl
ENSG00000116830
RefSeq RNA
NM_003594.4, XM_017002550.3, XM_017002551.3, XM_017002552.3, XM_017002555.3
RefSeq protein
NP_003585.3, XP_016858039.1, XP_016858040.1, XP_016858041.1, XP_016858044.1

This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing. [provided by RefSeq, Jul 2008].

Gene Ontology

Pathways

Thyroid hormone synthesis - Homo sapiens (human)Thyroid stimulating hormone (TSH) signaling pathwayThyroid hormones production and their peripheral downstream signaling effects

via MyGene.info

Gene · Ensembl

transcription termination factor 2

Symbol
TTF2
Biotype
Protein coding
Organism
Homo sapiens
Location
1:117,060,285-117,107,453
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
HomoloGene ID
37826
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/8458
genomic end
117650075
genomic start
117060326
chromosome
human chromosome 1
cytogenetic location
1p13.1
expressed in
testicle
Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections
Contents
  • Interactions
  • References
  • Further reading

Transcription termination factor 2 is a protein that in humans is encoded by the TTF2 gene.

This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing.

Excerpted from Wikipedia’s “TTF2” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0