TWF1
Sign in to saveAlso known as A6, PTK9, twinfilin actin binding protein 1
Twinfilin-1 is a protein that in humans is encoded by the TWF1 gene. This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1.
Gene data
TWF1- Name
- twinfilin actin binding protein 1
- Type
- protein-coding
- Position
- 43,793,460–43,806,328 (−)
- Aliases
- A6, PTK9
- Ensembl
- ENSG00000151239
- RefSeq RNA
- NM_001242397.2, NM_002822.5, NM_198974.1, NR_073472.2, NR_073473.2
- RefSeq protein
- NP_001229326.1, NP_002813.3, XP_047285154.1, XP_047285155.1, XP_054228622.1
This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
twinfilin actin binding protein 1
- Symbol
- TWF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:43,793,460-43,806,328
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein TWF1 PDB 1m4j.png
Show 5 more facts
- HomoloGene ID
- 48140
- exact match
- identifiers.org/ncbigene/5756
- genomic end
- 43806328
- genomic start
- 44187526
- cytogenetic location
- 12q12
Sources (4)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
Twinfilin-1 is a protein that in humans is encoded by the TWF1 gene. This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1.
==References==