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type 2 diabetes
Sign in to saveAlso known as NIDDM, non-insulin-dependent diabetes mellitus, type II diabetes mellitus, type 2 diabetes mellitus, diabetes (type 2), adult-onset diabetes, diabetes mellitus type 2, rare insulin-independent diabetes mellitus
type of diabetes mellitus with high blood sugar and insulin resistance
OverviewAI-generated
Type 2 diabetes is a medical condition classified under the broader category of diabetes mellitus type 2. It is identified in the International Classification of Primary Care 2 by the code T90. In the ICD-10 system, a specific manifestation is named Type 2 diabetes mellitus with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC). The condition is also associated with the NCI Thesaurus identifier C26747.
The subject has been the focus of extensive research and clinical activity. A search for type 2 diabetes in PubMed yields 278,237 results, while ClinicalTrials.gov lists 11,674 related entries. Within the Vinony graph, the topic is referenced by 1,568 other encyclopedia articles.
Synthesized by Vinony from 10 facts across 5 sources: Wikidata, PubMed, ClinicalTrials.gov, Medline, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Health references
- ICD-10
- E11.00 — Type 2 diabetes mellitus with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC)
- MedlinePlus
- Consumer health page →
Research
278,237 papers- Pathophysiology of Type 2 Diabetes Mellitus.ReviewInternational journal of molecular sciences · 2020Galicia-Garcia U, Benito-Vicente A, Jebari S et al.DOI: 10.3390/ijms21176275
- Type 2 Diabetes Mellitus and Cognitive Impairment.ReviewActa medica Indonesiana · 2021Damanik J, Yunir E
- Pharmacological approaches to the prevention of type 2 diabetes mellitus.ReviewFrontiers in endocrinology · 2023Majety P, Lozada Orquera FA, Edem D et al.DOI: 10.3389/fendo.2023.1118848
- Early detection of diabetic nephropathy in patient with type 2 diabetes mellitus: A review of the literature.ReviewDiabetes & vascular disease research · 2021Thipsawat SDOI: 10.1177/14791641211058856
- Gut Microbiota: An Important Player in Type 2 Diabetes Mellitus.ReviewFrontiers in cellular and infection microbiology · 2022Zhou Z, Sun B, Yu D et al.DOI: 10.3389/fcimb.2022.834485
- Type 2 Diabetes Mellitus: A Review of Multi-Target Drugs.ReviewMolecules (Basel, Switzerland) · 2020Artasensi A, Pedretti A, Vistoli G et al.DOI: 10.3390/molecules25081987
- Management of Type 2 Diabetes Mellitus in Elderly Patients with Frailty and/or Sarcopenia.ReviewInternational journal of environmental research and public health · 2022Sanz-Cánovas J, López-Sampalo A, Cobos-Palacios L et al.DOI: 10.3390/ijerph19148677
- Type 1 and Type 2 Diabetes Mellitus: Commonalities, Differences and the Importance of Exercise and Nutrition.Nutrients · 2023Krause M, De Vito GDOI: 10.3390/nu15194279
via PubMed
Clinical Trials
11,674 registered- NAUNKNOWNPRuDENTE; Diabetes Prevention Via Exercise, Nutrition and TreatmentInstituto Nacional de Salud Publica, Mexico · NCT03194009
- NACOMPLETEDHealthy Eating and Active Living for Diabetes: Glycemic IndexAthabasca University · NCT03037099
- NACOMPLETEDSleep Loss and Energy Metabolism in People With Family History of Type 2 Diabetes.University of Chicago · NCT00724087
- PHASE2COMPLETEDTTA in Treatment of Diabetes and DyslipidemiaHaukeland University Hospital · NCT00605787
- PHASE2TERMINATEDARMOR (Analyzing Renal Mechanisms of Creatinine Excretion in Patients On tesaglitazaR)AstraZeneca · NCT00229684
- NAACTIVE_NOT_RECRUITINGContinuous Glucose Monitoring in Dialysis Patients With DiabetesBo Feldt-Rasmussen · NCT06641765
~30 min read
Encyclopedic overview
Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent urination, fatigue and unexplained weight loss. Other symptoms include increased hunger, having a sensation of pins and needles, and sores (wounds) that heal slowly. Symptoms often develop slowly. Long-term complications from high blood sugar include heart disease; stroke; diabetic retinopathy, which can result in blindness; kidney failure; and poor blood flow in the lower limbs, which may lead to amputations. A sudden onset of hyperosmolar hyperglycemic state may occur; however, ketoacidosis is uncommon.
Type 2 diabetes primarily occurs as a result of obesity and lack of exercise. Some people are genetically more at risk than others. Type 2 diabetes makes up about 90% of cases of diabetes, with the other 10% due primarily to type 1 diabetes and gestational diabetes.
Excerpted from Wikipedia’s “type 2 diabetes” article, available under the CC BY-SA 4.0 licence.