UBAP1
Sign in to saveAlso known as NAG20, UAP, UBAP, UBAP-1, ubiquitin associated protein 1, SPG80
Ubiquitin-associated protein 1 is a protein that in humans is encoded by the UBAP1 gene.
Gene data
UBAP1- Name
- ubiquitin associated protein 1
- Type
- protein-coding
- Aliases
- NAG20, SPG80, UAP, UBAP, UBAP-1
This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010].
via MyGene.info
Gene · Ensembl
ubiquitin associated protein 1
- Symbol
- UBAP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:34,179,005-34,252,523
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein UBAP1 PDB 1wgn.png
Show 5 more facts
- HomoloGene ID
- 9554
- exact match
- identifiers.org/ncbigene/51271
- genomic end
- 34252521
- genomic start
- 34179003
- cytogenetic location
- 9p13.3
Sources (4)
via Wikidata · CC0
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Article
2 sectionsContents
- References
- Further reading
Ubiquitin-associated protein 1 is a protein that in humans is encoded by the UBAP1 gene.
This gene is a member of the ubiquitin-associated domain (UBA) family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin-binding domain consisting of a compact three-helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Truncating Mutations in UBAP1 Cause Hereditary Spastic Paraplegia.