UCN3
Sign in to saveAlso known as SCP, SPC, UCNIII, urocortin 3
Urocortin-3 is a protein that, in humans, is encoded by the UCN3 gene. It belongs to the corticotropin-releasing hormone family.
Gene data
UCN3- Name
- urocortin 3
- Type
- protein-coding
- Aliases
- SCP, SPC, UCNIII
This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite. [provided by RefSeq, May 2016].
via MyGene.info
Gene · Ensembl
urocortin 3
- Symbol
- UCN3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:5,364,966-5,374,692
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein UCN3 PDB 2RMH.png
Show 5 more facts
- HomoloGene ID
- 49959
- exact match
- identifiers.org/ncbigene/114131
- genomic start
- 5364966
- genomic end
- 5416169
- cytogenetic location
- 10p15.1
Sources (3)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Function
- References
- Further reading
Urocortin-3 is a protein that, in humans, is encoded by the UCN3 gene. It belongs to the corticotropin-releasing hormone family.
== Function ==