UHMK1
Sign in to saveAlso known as KIS, KIST, P-CIP2, U2AF homology motif (UHM) kinase 1, U2AF homology motif kinase 1
U2AF homology motif (UHM) kinase 1, also known as UHMK1, is a protein which in humans is encoded by the UHMK1 gene.
Gene data
UHMK1- Name
- U2AF homology motif kinase 1
- Type
- protein-coding
- Aliases
- KIS, KIST, P-CIP2
The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].
via MyGene.info
Gene · Ensembl
U2AF homology motif kinase 1
- Symbol
- UHMK1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:162,497,251-162,529,631
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- exact match
- identifiers.org/ncbigene/127933
- HomoloGene ID
- 7801
- genomic end
- 162529631
- genomic start
- 162467041
- cytogenetic location
- 1q23.3
Sources (4)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
U2AF homology motif (UHM) kinase 1, also known as UHMK1, is a protein which in humans is encoded by the UHMK1 gene.
==Function==