UIMC1
Sign in to saveAlso known as RAP80, X2HRIP110, ubiquitin interaction motif containing 1
BRCA1-A complex subunit RAP80 is a protein that in humans is encoded by the UIMC1 gene.
Gene data
UIMC1- Name
- ubiquitin interaction motif containing 1
- Type
- protein-coding
- Aliases
- RAP80, X2HRIP110
This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015].
via MyGene.info
Gene · Ensembl
ubiquitin interaction motif containing 1
- Symbol
- UIMC1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:176,902,225-177,022,646
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 9455
- exact match
- identifiers.org/ncbigene/51720
- genomic end
- 176449634
- genomic start
- 176332006
- cytogenetic location
- 5q35.2
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Repair of DNA damage
- References
- Further reading
BRCA1-A complex subunit RAP80 is a protein that in humans is encoded by the UIMC1 gene.
==Repair of DNA damage==
Connections
Q180686
Entity
human chromosome 5
Entity
Ensembl genome database project
Entity
protein
Entity
Wikidata
Entity
gene
Entity
chromosome
Entity
digital object identifier
Entity
bibcode
Entity
human genome
Entity
Q229883
Entity
base pair
Entity
locus
Entity
gene expression
Entity
Online Mendelian Inheritance in Man
Entity
Protein Data Bank
Entity
Q22908627
Entity
Entrez
Entity
Q905695
Entity
BRCA1 DNA repair associated
Protein