Skip to content
Vinony
English
EnglishDeutschEspañolFrançaisItalianoNederlandsPortuguêsSvenskaالعربية
GeneQ18033156· pop 5· linked from 10 articles

USO1

Sign in to save

Also known as P115, TAP, VDP, USO1 vesicle transport factor

General vesicular transport factor p115 is a protein that in humans is encoded by the USO1 gene.

Gene data

USO1
Name
USO1 vesicle transport factor
Type
protein-coding
Position
75,724,522–75,814,290 (+)
Aliases
P115, TAP, VDP
Ensembl
ENSG00000138768
RefSeq RNA
NM_001290049.2, NM_003715.4, XM_006714396.5, XM_006714397.4, XM_054351145.1
RefSeq protein
NP_001276978.1, NP_003706.2, XP_006714459.1, XP_006714460.1, XP_054207120.1

The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014].

Gene Ontology

Pathways

Golgi Cisternae Pericentriolar Stack ReorganizationCell CycleER to Golgi Anterograde TransportMembrane TraffickingCOPII-mediated vesicle transportMetabolism of proteinsAsparagine N-linked glycosylationVesicle-mediated transportPost-translational protein modificationCOPI-mediated anterograde transport

via MyGene.info

Gene · Ensembl

USO1 vesicle transport factor

Symbol
USO1
Biotype
Protein coding
Organism
Homo sapiens
Location
4:75,724,522-75,814,290
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 7 more facts
HomoloGene ID
2754
exact match
identifiers.org/ncbigene/8615
found in taxon
Homo sapiens
genomic end
76735382
genomic start
75724577
chromosome
human chromosome 4
cytogenetic location
4q21.1
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

4 sections
Contents
  • Function
  • Interactions
  • References
  • Further reading

General vesicular transport factor p115 is a protein that in humans is encoded by the USO1 gene.

== Function ==

Excerpted from Wikipedia’s “USO1” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0