vaniprevir

Vaniprevir (MK-7009) is a macrocyclic hepatitis C virus (HCV) NS3/4A protease inhibitor, developed by Merck & Co., which is currently in clinical testing. In Japan, it was approved for treating hepatitis C in 2014 under the brand name Vanihep.

In the Vinony graph

Vinony's link graph records 101 inbound references to vaniprevir, and connects out to medication, influenza and digital object identifier.

Vinony files it under Acylsulfonamides, Cyclopropyl compounds and Drugs missing an ATC code.

Vinony links it to 6 Wikipedia language editions.

Chemical data

Formula: C38H55N5O9S
Molecular weight: 757.9 g/mol
IUPAC name: (1R,21S,24S)-21-tert-butyl-N-[(1R,2R)-1-(cyclopropylsulfonylcarbamoyl)-2-ethylcyclopropyl]-16,16-dimethyl-3,19,22-trioxo-2,18-dioxa-4,20,23-triazatetracyclo[21.2.1.14,7.06,11]heptacosa-6(11),7,9-triene-24-carboxamide
SMILES: CC[C@@H]1C[C@@]1(C(=O)NS(=O)(=O)C2CC2)NC(=O)[C@@H]3C[C@@H]4CN3C(=O)[C@@H](NC(=O)OCC(CCCCC5=C6CN(CC6=CC=C5)C(=O)O4)(C)C)C(C)(C)C
InChIKey: KUQWGLQLLVFLSM-ONAXAZCASA-N
XLogP: 5.1
Polar surface area: 189 Å²
H-bond donors: 3
H-bond acceptors: 9
Formal charge: 0

via PubChem

Wikidata facts

Subclass of: chemical compound
Mass: 757.372049

Show 4 more facts

isomeric SMILES: CC[C@@H]1C[C@@]1(C(=O)NS(=O)(=O)C2CC2)NC(=O)[C@@H]3C[C@@H]4CN3C(=O)[C@@H](NC(=O)OCC(CCCCC5=C6CN(CC6=CC=C5)C(=O)O4)(C)C)C(C)(C)C
canonical SMILES: CCC1CC1(C(=O)NS(=O)(=O)C2CC2)NC(=O)C3CC4CN3C(=O)C(NC(=O)OCC(CCCCC5=C6CN(CC6=CC=C5)C(=O)O4)(C)C)C(C)(C)C
chemical formula: C₃₈H₅₅N₅O₉S
Commons category: Vaniprevir

Sources (2)

via Wikidata · CC0

~1 min read