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moroxydine
Sign in to saveMoroxydine is an antiviral drug that was originally developed in the 1950s as an influenza treatment. It has potential applications against a number of RNA and DNA viruses. Structurally moroxydine is a heterocyclic biguanidine.
Chemical data
- Formula
- C6H13N5O
- Molecular weight
- 171.2 g/mol
- IUPAC name
- N-(diaminomethylidene)morpholine-4-carboximidamide
- SMILES
- C1COCCN1C(=N)N=C(N)N
- InChIKey
- KJHOZAZQWVKILO-UHFFFAOYSA-N
- XLogP
- -1.6
- Polar surface area
- 101 Ų
- H-bond donors
- 3
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- viral disease
via ChEMBL · EBI
Research
78 papers- Moroxydine: the story of a mislaid antiviral.Acta dermato-venereologica. Supplementum · 1994
- [Moroxydine].Deutsche medizinische Wochenschrift (1946) · 1980
- Antiviral modes of action of the novel compound GLY-15 containing pyrimidine heterocycle and moroxydine skeleton against tobacco mosaic virus.Pest management science · 2022
- Moroxydine hydrochloride inhibits grass carp reovirus replication and suppresses apoptosis in Ctenopharyngodon idella kidney cells.Antiviral research · 2016
- Quantification of water-soluble moroxydine hydrochloride residue using UPLC-MS/MS: Development and validation in 22 different complex plant-based food samples.Food chemistry · 2025
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 171.112
Show 4 more facts
- chemical formula
- C₆H₁₃N₅O
- canonical SMILES
- C1COCCN1C(=N)N=C(N)N
- isomeric SMILES
- NC(=N)/N=C(\N)/N1CCOCC1
- Commons category
- Moroxydine
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Moroxydine is an antiviral drug that was originally developed in the 1950s as an influenza treatment. It has potential applications against a number of RNA and DNA viruses. Structurally moroxydine is a heterocyclic biguanidine.
It was reported in March 2014 that three kindergartens in two provinces of China had been found to be secretly dosing their students with moroxydine hydrochloride to try to prevent them from becoming ill. The kindergartens are paid only for the days that pupils attend and wanted to ensure that they maximised their earnings. In 2019, the Food and Drug Administration discovered the presence of moroxydine in a male enhancement product that was already found to contain undeclared sildenafil.
Excerpted from Wikipedia’s “moroxydine” article, available under the CC BY-SA 4.0 licence.
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