Structure via PubChem · Public domain (PubChem)
imiquimod
Sign in to saveAlso known as R-837, 1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine, 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline, R 837, S-26308, Imiquimodum, Zartra
Imiquimod, sold under the brand name Aldara among others, is a medication that acts as an immune response modifier that is used to treat genital warts, superficial basal cell carcinoma, and actinic keratosis.
Key facts
- Drug.Watchedfields
- changed
- Drug.caption2
- 3D representation of an imiquimod molecule
- Drug.verifiedrevid
- 461936187
- Drug.image
- Imiquimod.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 180
- Drug.caption
- Molecular structure of imiquimod
- Drug.image2
- Imiquimod 3D.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Aldara, others
- Drug.MedlinePlus
- a698010
- Drug.licence_EU
- yes
- Drug.DailyMedID
- Imiquimod
- Drug.pregnancy_AU
- B1
- Drug.routes_of_administration
- Topical
- Drug.ATC_prefix
- D06
- Drug.ATC_suffix
- BB10
- Drug.legal_UK
- POM
via Wikipedia infobox
Chemical data
- Formula
- C14H16N4
- Molecular weight
- 240.3 g/mol
- IUPAC name
- 1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine
- SMILES
- CC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N
- InChIKey
- DOUYETYNHWVLEO-UHFFFAOYSA-N
- XLogP
- 2.6
- Polar surface area
- 56.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
6,309 papers- Imiquimod.Dermatologic clinics · 2003
- Imiquimod.Current opinion in infectious diseases · 2003
- Imiquimod for Anal High Grade Intraepithelial Neoplasia: A Systematic Review.Current oncology reports · 2025
- Imiquimod: a review.Journal of cutaneous medicine and surgery · 2002
- Imiquimod-Associated Pemphigus Foliaceus.American journal of therapeutics · 2022
via PubMed
~5 min read
Encyclopedic overview
7 sectionsContents
- Medical uses
- Side effects
- Mechanism of action
- History
- Research
- References
- External links
Imiquimod, sold under the brand name Aldara among others, is a medication that acts as an immune response modifier that is used to treat genital warts, superficial basal cell carcinoma, and actinic keratosis.
Scientists at 3M's pharmaceuticals division discovered the drug and 3M obtained the first FDA approval in 1997. As of 2015, imiquimod is generic and is available worldwide under many brands. In 2021, it was the 290th most commonly prescribed medication in the United States, with more than 600,000 prescriptions.
Excerpted from Wikipedia’s “imiquimod” article, available under the CC BY-SA 4.0 licence.