WI-38
Sign in to saveAlso known as WI 38, WI38, Wistar Institute-38, AG06814E, AG06814G, AG06814H, AG06814-J
thumb|WI-38 cells (Left: in high density. Right: in low density) WI-38 is a diploid human cell line composed of fibroblasts derived from lung tissue of a 3-month-gestation female fetus. The fetus came from a legal abortion performed in Sweden in 1962. The cell line was isolated by Leonard Hayflick the same year, and has been used extensively in scientific research, with applications ranging from developing important theories in molecular biology and aging to the production of most human virus vaccines. The uses of this cell line in human virus vaccine production is estimated to have saved the
In the Vinony graph
Vinony's link graph records 10 inbound references to WI-38, and connects out to Pennsylvania, Philadelphia and chromosome.
It sits within the topics 1960s establishments in Pennsylvania, 1960s in biology and Cellular senescence.
Vinony links it to 7 Wikipedia language editions.
Wikidata facts
Show 3 more facts
- discoverer or inventor
- Leonard Hayflick
- exact match
- purl.obolibrary.org/obo/CLO_0035534
- derived from organism type
- Homo sapiens
Sources (2)
via Wikidata · CC0
~4 min read
Encyclopedic overview
6 sectionsContents
- History
- Applications
- Genome sequence
- See also
- References
- External links
thumb|WI-38 cells (Left: in high density. Right: in low density) WI-38 is a diploid human cell line composed of fibroblasts derived from lung tissue of a 3-month-gestation female fetus. The fetus came from a legal abortion performed in Sweden in 1962. The cell line was isolated by Leonard Hayflick the same year, and has been used extensively in scientific research, with applications ranging from developing important theories in molecular biology and aging to the production of most human virus vaccines. The uses of this cell line in human virus vaccine production is estimated to have saved the lives of millions of people.
==History== The WI-38 cell line stemmed from earlier work by Hayflick growing human cell cultures.
Excerpted from Wikipedia’s “WI-38” article, available under the CC BY-SA 4.0 licence.