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fibroblast
Sign in to saveAlso known as fibroblasts
A fibroblast is a type of biological cell typically with a spindle shape that synthesizes the extracellular matrix and collagen, produces the structural framework (stroma) for animal tissues, and plays a critical role in wound healing. Fibroblasts are the most common cells of connective tissue in animals.
Key facts
- Cell.Name
- Fibroblast
- Cell.Latin
- fibroblastus
- Cell.Image
- NIH 3T3.jpg
- Cell.Caption
- NIH/3T3 Fibroblasts in cell culture
- Cell.Function
- Extracellular matrix and collagen creation
- Cell.Location
- Connective tissue
via Wikipedia infobox
Research
403,995 papers- A single-cell and spatial genomics atlas of human skin fibroblasts reveals shared disease-related fibroblast subtypes across tissues.Nature immunology · 2025
- Lymph node fibroblast-produced extracellular matrix shapes immune function.Trends in immunology · 2025
- Different fibroblast subtypes propel spatially defined ileal inflammation through TNFR1 signalling in murine ileitis.Nature communications · 2025
- Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer.Cancer cell · 2022
- The fibroblast epigenome underlies SS18::SSX-mediated transformation in synovial sarcoma.Nature communications · 2025
via PubMed
Wikidata facts
- Image
- Fibroblast focus.jpg
Show 2 more facts
- Commons category
- Fibroblasts
- native label
- fibroblastus
via Wikidata · CC0
~8 min read
Article
11 sectionsContents
- Structure
- Relationship with fibrocytes
- Development
- Function
- Inflammation
- Tumour mediation
- Use of fibroblasts as feeder cells
- Host immune response
- See also
- References
- External links
A fibroblast is a type of biological cell typically with a spindle shape that synthesizes the extracellular matrix and collagen, produces the structural framework (stroma) for animal tissues, and plays a critical role in wound healing. Fibroblasts are the most common cells of connective tissue in animals.
== Structure ==
Gallery (2)
Connections
connective tissue
Entity
mesenchyme
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elastic fiber
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Latin
Entity
chicken
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blood
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cell
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bone
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International Standard Book Number
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enzyme
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metabolism
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tissue
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digital object identifier
Entity
nucleus
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International Standard Serial Number
Entity
cartilage
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stem cell
Entity
cytoplasm
Entity
endoplasmic reticulum
Entity
epithelium
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