WIPI1
Sign in to saveAlso known as ATG18, ATG18A, WIPI49, WD repeat domain, phosphoinositide interacting 1
WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1), also known as Atg18 protein homolog (ATG18) and WD40 repeat protein interacting with phosphoinositides of 49 kDa (WIPI 49 kDa), is a protein that in humans is encoded by the WIPI1 gene.
In the Vinony graph
Within Vinony's link graph, WIPI1 is referenced by 5 other articles, and connects out to PubMed, human chromosome 17 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 17.
Its subject is documented across 5 Wikipedia language editions.
Gene data
WIPI1- Name
- WD repeat domain, phosphoinositide interacting 1
- Type
- protein-coding
- Position
- 68,420,948–68,457,563 (−)
- Aliases
- ATG18, ATG18A, WIPI49
- Ensembl
- ENSG00000070540
- RefSeq RNA
- NM_001320772.2, NM_017983.7, NR_135470.2, NR_135471.2, XM_017024808.2
- RefSeq protein
- NP_001307701.1, NP_060453.3, XP_016880297.1, XP_054172569.1
This gene encodes a WD40 repeat protein. Members of the WD40 repeat family are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
WD repeat domain, phosphoinositide interacting 1
- Symbol
- WIPI1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:68,420,948-68,457,563
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 117983
- genomic end
- 66453654
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/55062
- genomic start
- 66417089
- chromosome
- human chromosome 17
- cytogenetic location
- 17q24.2
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Structure and function
- See also
- References
- Further reading
WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1), also known as Atg18 protein homolog (ATG18) and WD40 repeat protein interacting with phosphoinositides of 49 kDa (WIPI 49 kDa), is a protein that in humans is encoded by the WIPI1 gene.
== Structure and function ==
Excerpted from Wikipedia’s “WIPI1” article, available under the CC BY-SA 4.0 licence.