XAF1
Sign in to saveAlso known as BIRC4BP, HSXIAPAF1, XIAPAF1, XIAP associated factor 1
XIAP-associated factor 1 is a protein that in humans is encoded by the XAF1 gene.
Gene data
XAF1- Name
- XIAP associated factor 1
- Type
- protein-coding
- Position
- 6,755,375–6,775,647 (+)
- Aliases
- BIRC4BP, HSXIAPAF1, XIAPAF1
- Ensembl
- ENSG00000132530
- RefSeq RNA
- NM_001353134.2, NM_001353135.1, NM_001353136.2, NM_001353137.2, NM_001353138.2
- RefSeq protein
- NP_001340063.1, NP_001340064.1, NP_001340065.1, NP_001340066.1, NP_001340067.1
This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
XIAP associated factor 1
- Symbol
- XAF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:6,755,375-6,775,647
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
XIAP-associated factor 1 is a protein that in humans is encoded by the XAF1 gene.
== Function ==
Excerpted from Wikipedia’s “XAF1” article, available under the CC BY-SA 4.0 licence.