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zavegepant

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Also known as vazegepant, BHV-3500, BMS-742413, N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide

Zavegepant, sold under the brand name Zavzpret, is a medication used for the treatment of migraine. Zavegepant is a calcitonin gene-related peptide receptor antagonist. It is sprayed into the nose. It is sold by Pfizer.

Key facts

Drug.image
Zavegepant.svg
Drug.image_class
skin-invert-image
Drug.tradename
Zavzpret
Drug.DailyMedID
Zavegepant
Drug.routes_of_administration
Nasal
Drug.class
Calcitonin gene-related peptide receptor antagonist
Drug.ATC_prefix
N02
Drug.ATC_suffix
CD08
Drug.legal_US
Rx-only
Drug.index2_label
as HCl
Drug.CAS_number
1337918-83-8
Drug.CAS_number2
1414976-20-7
Drug.PubChem
53472683
Drug.PubChem2
134819878
Drug.DrugBank
DB15688
Drug.ChemSpiderID
30814207
Drug.UNII
ODU3ZAZ94J
Drug.UNII2
000QCM6HAL

via Wikipedia infobox

Wikidata facts

Mass
638.3692873320001
Show 4 more facts
canonical SMILES
CC1=CC(=CC2=C1NN=C2)CC(C(=O)N3CCN(CC3)C4CCN(CC4)C)NC(=O)N5CCC(CC5)C6=CC7=CC=CC=C7NC6=O
isomeric SMILES
CC1=CC(=CC2=C1NN=C2)C[C@H](C(=O)N3CCN(CC3)C4CCN(CC4)C)NC(=O)N5CCC(CC5)C6=CC7=CC=CC=C7NC6=O
Commons category
Zavegepant
chemical formula
C₃₆H₄₆N₈O₃
Sources (1)

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Article

4 sections
Contents
  • Medical uses
  • References
  • Further reading
  • External links

Zavegepant, sold under the brand name Zavzpret, is a medication used for the treatment of migraine. Zavegepant is a calcitonin gene-related peptide receptor antagonist. It is sprayed into the nose. It is sold by Pfizer.

The most common adverse reactions include taste disorders, nausea, nasal discomfort, and vomiting.

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