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3-fluoroamphetamine

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3-Fluoroamphetamine (3-FA; PAL-353) is a stimulant drug from the amphetamine family which acts as a monoamine releaser with similar potency to methamphetamine but more selectivity for dopamine and norepinephrine release over serotonin. It is self-administered by mice to a similar extent to related drugs such as 4-fluoroamphetamine and 3-methylamphetamine.

Wikidata facts

Mass
153.095
Show 3 more facts
chemical formula
C₉H₁₂FN
canonical SMILES
CC(CC1=CC(=CC=C1)F)N
Commons category
3-Fluoroamphetamine
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7 sections
Contents
  • Chemistry
  • Pharmacology
  • Molecular mechanism
  • Uses
  • Legal status
  • See also
  • References

3-Fluoroamphetamine (3-FA; PAL-353) is a stimulant drug from the amphetamine family which acts as a monoamine releaser with similar potency to methamphetamine but more selectivity for dopamine and norepinephrine release over serotonin. It is self-administered by mice to a similar extent to related drugs such as 4-fluoroamphetamine and 3-methylamphetamine.

3-Fluoroamphetamine has been used as a designer drug in several studies to mimic the effects of illegal amphetamines. It has also appeared on the drug market for recreational use as an amphetamine alternative, as was reported in January 2009 to the European Early Warning System by Belgium. Little is known about the exact history of this compound.

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