amfetaminil

Amfetaminil (also known as amphetaminil, '''N-cyanobenzylamphetamine, and AN-1; brand name Aponeuron''') is a stimulant drug derived from amphetamine, which was developed in the 1970s and used for the treatment of obesity, ADHD, and narcolepsy. It has largely been withdrawn from clinical use following problems with abuse. The drug is a prodrug to amphetamine.

Chemical data

Formula: C17H18N2
Molecular weight: 250.34 g/mol
IUPAC name: 2-phenyl-2-(1-phenylpropan-2-ylamino)acetonitrile
SMILES: CC(CC1=CC=CC=C1)NC(C#N)C2=CC=CC=C2
InChIKey: NFHVTCJKAHYEQN-UHFFFAOYSA-N
XLogP: 3.7
Polar surface area: 35.8 Å²
H-bond donors: 1
H-bond acceptors: 2
Formal charge: 0

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Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

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Wikidata facts

Subclass of: chemical compound
Mass: 250.147

Show 3 more facts

chemical formula: C₁₇H₁₈N₂
canonical SMILES: CC(CC1=CC=CC=C1)NC(C#N)C2=CC=CC=C2
Commons category: Amphetaminil

Sources (2)

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Encyclopedic overview

6 sections

Contents

Chemistry
Stereochemistry
Synthesis
See also
References
External links

Amfetaminil (also known as amphetaminil, '''N-cyanobenzylamphetamine, and AN-1; brand name Aponeuron') is a stimulant drug derived from amphetamine, which was developed in the 1970s and used for the treatment of obesity, ADHD, and narcolepsy. It has largely been withdrawn from clinical use following problems with abuse. The drug is a prodrug to amphetamine.

==Chemistry== ===Stereochemistry=== Amfetaminil is a molecule with two stereogenic centers. Thus, four different stereoisomers exist:

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