amfetaminil

Amfetaminil (also known as amphetaminil, '''N-cyanobenzylamphetamine, and AN-1; brand name Aponeuron''') is a stimulant drug derived from amphetamine, which was developed in the 1970s and used for the treatment of obesity, ADHD, and narcolepsy. It has largely been withdrawn from clinical use following problems with abuse. The drug is a prodrug to amphetamine.

In the Vinony graph

Vinony's link graph records 1,522 inbound references to amfetaminil, and connects out to amphetamines, phenethylamine and N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine.

Vinony files it under Anorectics, Benzyl compounds and Chemical pages without DrugBank identifier.

Vinony links it to 8 Wikipedia language editions.

Chemical data

Formula: C17H18N2
Molecular weight: 250.34 g/mol
IUPAC name: 2-phenyl-2-(1-phenylpropan-2-ylamino)acetonitrile
SMILES: CC(CC1=CC=CC=C1)NC(C#N)C2=CC=CC=C2
InChIKey: NFHVTCJKAHYEQN-UHFFFAOYSA-N
XLogP: 3.7
Polar surface area: 35.8 Å²
H-bond donors: 1
H-bond acceptors: 2
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 250.147

Show 3 more facts

chemical formula: C₁₇H₁₈N₂
canonical SMILES: CC(CC1=CC=CC=C1)NC(C#N)C2=CC=CC=C2
Commons category: Amphetaminil

Sources (2)

via Wikidata · CC0

~2 min read

Encyclopedic overview

6 sections

Contents

Chemistry
Stereochemistry
Synthesis
See also
References
External links

Amfetaminil (also known as amphetaminil, '''N-cyanobenzylamphetamine, and AN-1; brand name Aponeuron') is a stimulant drug derived from amphetamine, which was developed in the 1970s and used for the treatment of obesity, ADHD, and narcolepsy. It has largely been withdrawn from clinical use following problems with abuse. The drug is a prodrug to amphetamine.

==Chemistry== ===Stereochemistry=== Amfetaminil is a molecule with two stereogenic centers. Thus, four different stereoisomers exist:

Excerpted from Wikipedia’s “amfetaminil” article, available under the CC BY-SA 4.0 licence.