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5-HO-DiPT

Structure via PubChem · Public domain (PubChem)

EntityQ15405290· pop 5· linked from 514 articles

5-HO-DiPT, also known as '5-hydroxy-N,N-di-iso-propyltryptamine', is a tryptamine derivative which acts as a serotonin receptor agonist. It is primarily known as a metabolite of the better known psychoactive drug 5-MeO-DiPT, but 5-HO-DiPT has also rarely been encountered as a designer drug in its own right. Tests in vitro show 5-HO-DiPT to have high serotonin 5-HT2A receptor affinity and good selectivity over the serotonin 5-HT1A receptor, while being more lipophilic than the related drug bufotenine (5-HO-DMT), which produces primarily peripheral effects.

Chemical data

Formula
C16H24N2O
Molecular weight
260.37 g/mol
IUPAC name
3-[2-[di(propan-2-yl)amino]ethyl]-1H-indol-5-ol
SMILES
CC(C)N(CCC1=CNC2=C1C=C(C=C2)O)C(C)C
InChIKey
HWOLNTJLIUHEOG-UHFFFAOYSA-N
XLogP
2.8
Polar surface area
39.3 Ų
H-bond donors
2
H-bond acceptors
2
Formal charge
0

via PubChem

Wikidata facts

Mass
260.188863
Show 3 more facts
chemical formula
C₁₆H₂₄N₂O
canonical SMILES
CC(C)N(CCC1=CNC2=C1C=C(C=C2)O)C(C)C
Commons category
5-HO-DIPT
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

6 sections
Contents
  • Interactions
  • Chemistry
  • Analogues
  • See also
  • References
  • External links

5-HO-DiPT, also known as '5-hydroxy-N,N-di-iso-propyltryptamine', is a tryptamine derivative which acts as a serotonin receptor agonist. It is primarily known as a metabolite of the better known psychoactive drug 5-MeO-DiPT, but 5-HO-DiPT has also rarely been encountered as a designer drug in its own right. Tests in vitro show 5-HO-DiPT to have high serotonin 5-HT2A receptor affinity and good selectivity over the serotonin 5-HT1A receptor, while being more lipophilic than the related drug bufotenine (5-HO-DMT), which produces primarily peripheral effects.

==Interactions==

Excerpted from Wikipedia’s “5-HO-DiPT” article, available under the CC BY-SA 4.0 licence.

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