Structure via PubChem · Public domain (PubChem)
FGIN-127
Sign in to saveAlso known as 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide
FGIN-1-27 is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO. It is thought to produce anxiolytic effects by stimulating steroidogenesis of neuroactive steroids such as allopregnanolone.
Chemical data
- Formula
- C28H37FN2O
- Molecular weight
- 436.6 g/mol
- IUPAC name
- 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide
- SMILES
- CCCCCCN(CCCCCC)C(=O)CC1=C(NC2=CC=CC=C21)C3=CC=C(C=C3)F
- InChIKey
- VUWXAQFLTSBUDB-UHFFFAOYSA-N
- XLogP
- 7.9
- Polar surface area
- 36.1 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 436.289
Show 2 more facts
- canonical SMILES
- CCCCCCN(CCCCCC)C(=O)CC1=C(NC2=CC=CC=C21)C3=CC=C(C=C3)F
- chemical formula
- C₂₈H₃₇FN₂O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
FGIN-1-27 is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO. It is thought to produce anxiolytic effects by stimulating steroidogenesis of neuroactive steroids such as allopregnanolone.
== References ==
Excerpted from Wikipedia’s “FGIN-127” article, available under the CC BY-SA 4.0 licence.