actinonin

Also known as 2-[(Formyl-Hydroxy-Amino)-Methyl]-Heptanoic Acid [1-(2-Hydroxymethyl-Pyrrolidine-1-Carbonyl)-2-Methyl-Propyl]-Amide

Actinonin is a naturally occurring antibacterial agent that has demonstrated anti-tumor activity.

In the Vinony graph

Vinony's link graph records 2 inbound references to actinonin, and connects out to bacteria, enzyme and antibiotic.

It sits within the topics Chembox image size set and Hydroxamic acids.

Vinony links it to 5 Wikipedia language editions.

Chemical data

Formula: C19H35N3O5
Molecular weight: 385.5 g/mol
IUPAC name: (2R)-N'-hydroxy-N-[(2S)-1-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]-2-pentylbutanediamide
SMILES: CCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1CO
InChIKey: XJLATMLVMSFZBN-VYDXJSESSA-N
XLogP: 1.5
Polar surface area: 119 Å²
H-bond donors: 4
H-bond acceptors: 5
Formal charge: 0

via PubChem

Drug data · ChEMBL

Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 385.258

Show 5 more facts

chemical formula: C₁₉H₃₅N₃O₅
canonical SMILES: CCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1CCCC1CO
isomeric SMILES: CCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1CO
subject has role: antibiotic
found in taxon: Streptomyces

Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

1 sections

Contents

References

{{Chembox | Verifiedfields = changed | verifiedrevid = 477241675 | ImageFile = Actinonin.svg | ImageSize = 200px | PIN = (2R)-N4-Hydroxy-N1-{(2S)-1-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl}-2-pentylbutanediamide | OtherNames = HONH-Val-Pro-OH (IUPAC peptide linear) |Section1= |Section2= |Section3= }} Actinonin is a naturally occurring antibacterial agent that has demonstrated anti-tumor activity.

Actiononin has been shown to inhibit the enzyme peptide deformylase, which is essential in bacteria.

Excerpted from Wikipedia’s “actinonin” article, available under the CC BY-SA 4.0 licence.