rokitamycin

Rokitamycin is a macrolide antibiotic synthesized from strains of Streptomyces kitasatoensis.

In the Vinony graph

Vinony's link graph records 110 inbound references to rokitamycin, and connects out to neomycin, antibiotic and ethanol.

Vinony files it under Chemical pages without DrugBank identifier, Drugboxes which contain changes to verified fields and Drugs with no legal status.

Vinony links it to 8 Wikipedia language editions.

Chemical data

Formula: C42H69NO15
Molecular weight: 828 g/mol
IUPAC name: [(2S,3S,4R,6S)-6-[(2R,3S,4R,5R,6S)-6-[[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy-2,4-dimethyl-4-propanoyloxyoxan-3-yl] butanoate
SMILES: CCCC(=O)O[C@H]1[C@@H](O[C@H](C[C@@]1(C)OC(=O)CC)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2N(C)C)O)O[C@H]3[C@H](C[C@H]([C@H](/C=C/C=C/C[C@H](OC(=O)C[C@H]([C@@H]3OC)O)C)O)C)CC=O)C)C
InChIKey: VYWWNRMSAPEJLS-MDWYKHENSA-N
XLogP: 3
Polar surface area: 206 Å²
H-bond donors: 3
H-bond acceptors: 16
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule
Indications: bacterial disease

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 827.467

Show 3 more facts

chemical formula: C₄₂H₆₉NO₁₅
isomeric SMILES: CCCC(=O)O[C@H]1[C@@H](O[C@H](C[C@@]1(C)OC(=O)CC)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2N(C)C)O)O[C@H]3[C@H](C[C@H]([C@H](/C=C/C=C/C[C@H](OC(=O)C[C@H]([C@@H]3OC)O)C)O)C)CC=O)C)C
canonical SMILES: CCCC(=O)OC1C(OC(CC1(C)OC(=O)CC)OC2C(OC(C(C2N(C)C)O)OC3C(CC(C(C=CC=CCC(OC(=O)CC(C3OC)O)C)O)C)CC=O)C)C

Sources (2)

via Wikidata · CC0

~2 min read

Encyclopedic overview

2 sections

Contents

References
External links

{{Drugbox | Verifiedfields = changed | verifiedrevid = 464383231 | IUPAC_name = (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy}-2,4-dimethyl-4-propoxyoxan-3-yl butanoate | image = rokitamycin.png | image_class = skin-invert-image

Excerpted from Wikipedia’s “rokitamycin” article, available under the CC BY-SA 4.0 licence.