
lymecycline
Sign in to saveAlso known as N6-((4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamido)methyl)lysine, N-Lysinomethyltetracycline, Limeciclina, Tetracycline-L-methylene lysine, Tetracycline-L-methylenelysine, N(2)-(((+)-5-Amino-5-carboxypentylamino)methyl)tetracycline, (+)-N-(5-Amino-5-carboxypentylaminomethyl)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide, Lymecyclinum
Lymecycline is a tetracycline broad-spectrum antibiotic. It is approximately 5,000 times more soluble than tetracycline base and is unique amongst tetracyclines in that it is absorbed by an active transport process across the intestinal wall, making use of the same fast and efficient mechanism by which carbohydrates are absorbed.
Research
201 papers- LYMECYCLINE.British medical journal · 1965
- Lymecycline reverses acquired EGFR-TKI resistance in non-small-cell lung cancer by targeting GRB2.Pharmacological research · 2020
- Pharmacokinetics and pharmacodynamics of the tetracyclines including glycylcyclines.The Journal of antimicrobial chemotherapy · 2006
- Pseudotumor cerebri syndrome secondary to lymecycline therapy.European journal of ophthalmology · 2022
- Lymecycline in the treatment of acne: an efficacious, safe and cost-effective alternative to minocycline.European journal of dermatology : EJD · 2003
via PubMed
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Encyclopedic overview
6 sectionsContents
- History
- Indications
- Acne
- Side effects
- See also
- References
Lymecycline is a tetracycline broad-spectrum antibiotic. It is approximately 5,000 times more soluble than tetracycline base and is unique amongst tetracyclines in that it is absorbed by an active transport process across the intestinal wall, making use of the same fast and efficient mechanism by which carbohydrates are absorbed.
The greater absorption of lymecycline allows for lower dosages to be used; the standard dose of 408 mg is equivalent to 300 mg tetracycline base and, in its action, to 500 mg tetracycline hydrochloride. Lymecycline, unlike tetracycline hydrochloride, is soluble at all physiological pH values.
Excerpted from Wikipedia’s “lymecycline” article, available under the CC BY-SA 4.0 licence.
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