Structure via PubChem · Public domain (PubChem)
sutezolid
Sign in to saveSutezolid is an investigational new drug that is being evaluated for the treatment of extensively drug-resistant tuberculosis. It differs from linezolid by replacement of the morpholine oxygen with a sulfur atom. Like linezolid, sutezolid is a bacterial protein synthesis inhibitor. In preclinical studies, sutezolid demonstrated superior antituberculosis activity compared to linezolid.
Chemical data
- Formula
- C16H20FN3O3S
- Molecular weight
- 353.4 g/mol
- IUPAC name
- N-[[(5S)-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide
- SMILES
- CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCSCC3)F
- InChIKey
- FNDDDNOJWPQCBZ-ZDUSSCGKSA-N
- XLogP
- 1.5
- Polar surface area
- 87.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- pulmonary tuberculosis, tuberculosis
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 353.121
Show 3 more facts
- chemical formula
- C₁₆H₂₀FN₃O₃S
- canonical SMILES
- CC(=O)NCC1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCSCC3)F
- isomeric SMILES
- CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCSCC3)F
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Sutezolid is an investigational new drug that is being evaluated for the treatment of extensively drug-resistant tuberculosis. It differs from linezolid by replacement of the morpholine oxygen with a sulfur atom. Like linezolid, sutezolid is a bacterial protein synthesis inhibitor. In preclinical studies, sutezolid demonstrated superior antituberculosis activity compared to linezolid.
== References ==
Excerpted from Wikipedia’s “sutezolid” article, available under the CC BY-SA 4.0 licence.