AGER
Sign in to saveAlso known as RAGE, SCARJ1, advanced glycosylation end product-specific receptor, advanced glycosylation end-product specific receptor, sRAGE
protein-coding gene in the species Homo sapiens
Gene data
AGER- Name
- advanced glycosylation end-product specific receptor
- Type
- protein-coding
- Position
- 32,180,963–32,184,344 (−)
- Aliases
- RAGE, SCARJ1, sRAGE
- Ensembl
- ENSG00000230514
- RefSeq RNA
- NM_001136.5, NM_001206929.2, NM_001206932.2, NM_001206934.2, NM_001206936.2
- RefSeq protein
- NP_001127.1, NP_001193858.1, NP_001193861.1, NP_001193863.1, NP_001193865.1
The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
advanced glycosylation end-product specific receptor
- Symbol
- AGER
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HSCHR6_MHC_SSTO_CTG1:3,497,175-3,500,531
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 6 more facts
- HomoloGene ID
- 883
- exact match
- identifiers.org/ncbigene/177
- cytogenetic location
- 6p21.32
- genomic start
- 32148745
- genomic end
- 32184322
- Commons category
- RAGE (receptor)
Sources (3)
via Wikidata · CC0