S100A2

Also known as CAN19, S100L, S100 calcium binding protein A2

S100 calcium-binding protein A2 (S100A2) is a protein that in humans is encoded by the S100A2 gene and it is located on chromosome 1q21 with other S100 proteins.

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Vinony's link graph records 3 inbound references to S100A2, and connects out to PubMed, cancer and protein.

It sits within the topics Human genes and S100 proteins.

Vinony links it to 5 Wikipedia language editions.

Gene data

S100A2

Name: S100 calcium binding protein A2
Type: protein-coding
Position: 153,560,950–153,586,676 (−)
Aliases: CAN19, S100L
Ensembl: ENSG00000196754
RefSeq RNA: NM_001366406.1, NM_001366407.1, NM_005978.4, XM_047427373.1, XM_054338109.1
RefSeq protein: NP_001353335.1, NP_001353336.1, NP_005969.2, XP_047283329.1, XP_054194084.1

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

endothelial cell migration endothelial cell migration

Molecular function

calcium ion binding calcium ion binding calcium ion binding protein binding identical protein binding identical protein binding transition metal ion binding calcium-dependent protein binding

Pathways

Vitamin D Receptor Pathway

via MyGene.info

Wikidata facts

Instance of: gene
Image: Protein S100A2 PDB 2RGI.png

Show 5 more facts

HomoloGene ID: 48389
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/6273
cytogenetic location: 1q21.3
expressed in: nipple

Sources (3)

via Wikidata · CC0

~2 min read

Encyclopedic overview

5 sections

Contents

Tissue and subcellular distribution
Function
Clinical significance
References
Further reading

S100 calcium-binding protein A2 (S100A2) is a protein that in humans is encoded by the S100A2 gene and it is located on chromosome 1q21 with other S100 proteins.

== Tissue and subcellular distribution ==

Excerpted from Wikipedia’s “S100A2” article, available under the CC BY-SA 4.0 licence.