S100A9

Also known as L1AG, LIAG, 60B8AG, CAGB, CFAG, CGLB, MAC387, MIF

S100 calcium-binding protein A9 (S100A9) also known as migration inhibitory factor-related protein 14 (MRP14) or calgranulin B is a protein that in humans is encoded by the S100A9 gene.

Gene data

S100A9

Name: S100 calcium binding protein A9
Type: protein-coding
Aliases: 60B8AG, CAGB, CFAG, CGLB, L1AG, LIAG, MAC387, MIF, MRP14, NIF

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. This antimicrobial protein exhibits antifungal and antibacterial activity. [provided by RefSeq, Nov 2014].

via MyGene.info

Gene · Ensembl

S100 calcium binding protein A9

Symbol: S100A9
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:153,357,767-153,361,036
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein S100A9 PDB 1irj.png

Show 5 more facts

HomoloGene ID: 2227
exact match: identifiers.org/ncbigene/6280
genomic end: 153361023
genomic start: 153330330
cytogenetic location: 1q21.3

Sources (6)

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Article

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Contents

Function
Clinical significance
Animal studies
See also
References
Further reading

S100 calcium-binding protein A9 (S100A9) also known as migration inhibitory factor-related protein 14 (MRP14) or calgranulin B is a protein that in humans is encoded by the S100A9 gene.

The proteins S100A8 and S100A9 form a heterodimer called calprotectin.