aglepristone

Also known as (8S,11R,13S,14S,17R)-11-[4-(dimethylamino)phenyl]-17-hydroxy-13-methyl-17-[(Z)-prop-1-enyl]-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one

Aglepristone () (brand name Alizin; former developmental code names RU-46534, RU-534) is a synthetic, steroidal antiprogestogen related to mifepristone. Aglepristone, similarly to mifepristone, also possesses some antiglucocorticoid activity. Aglepristone is used as an abortifacent, to induce parturition, and as a treatment for mammary hyperplasia and pyometra. It is only used in cats and dogs. == See also == Lilopristone Onapristone Telapristone Toripristone

In the Vinony graph

Within Vinony's link graph, aglepristone is referenced by 602 other articles, and connects out to mometasone furoate, fludrocortisone and ulipristal acetate.

It sits within the topics Abortifacients, Alkene derivatives and Antiglucocorticoids.

Its subject is documented across 12 Wikipedia language editions.

Chemical data

Formula: C29H37NO2
Molecular weight: 431.6 g/mol
IUPAC name: (8S,11R,13S,14S,17R)-11-[4-(dimethylamino)phenyl]-17-hydroxy-13-methyl-17-[(Z)-prop-1-enyl]-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
SMILES: C/C=C\[C@@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)C5=CC=C(C=C5)N(C)C)C)O
InChIKey: RTCKAOKDXNYXEH-FWSJOHTJSA-N
XLogP: 4
Polar surface area: 40.5 Å²
H-bond donors: 1
H-bond acceptors: 3
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 431.28242942400004

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canonical SMILES: CC=CC1(CCC2C1(CC(C3=C4CCC(=O)C=C4CCC23)C5=CC=C(C=C5)N(C)C)C)O
isomeric SMILES: C/C=C\[C@@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)C5=CC=C(C=C5)N(C)C)C)O
chemical formula: C₂₉H₃₇NO₂

Sources (2)

via Wikidata · CC0

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