cortivazol
Sign in to saveCortivazol is a high-affinity agonist ligand for the glucocorticoid receptor and consequently is classified as a glucocorticoid.
Research
70 papers- Cortivazol mediated induction of glucocorticoid receptor messenger ribonucleic acid in wild-type and dexamethasone-resistant human leukemic (CEM) cells.The Journal of steroid biochemistry and molecular biology · 1991
- Cortivazol increases glucocorticoid receptor expression and inhibits growth of hamster pancreatic cancer (H2T) in vivo.Pancreas · 1993
- [3H]cortivazol: a unique high affinity ligand for the glucocorticoid receptor.Endocrinology · 1985
- Four cases of coccygeal disk calcification after cortivazol injection.Joint bone spine · 2009
- The distinct agonistic properties of the phenylpyrazolosteroid cortivazol reveal interdomain communication within the glucocorticoid receptor.Molecular endocrinology (Baltimore, Md.) · 2005
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 530.278
- Has use
- medication
Show 4 more facts
- chemical formula
- C₃₂H₃₈N₂O₅
- canonical SMILES
- CC1CC2C3C=C(C4=CC5=C(CC4(C3C(CC2(C1(C(=O)COC(=O)C)O)C)O)C)C=NN5C6=CC=CC=C6)C
- isomeric SMILES
- C[C@@H]1C[C@H]2[C@@H]3C=C(C4=CC5=C(C[C@@]4([C@H]3[C@H](C[C@@]2([C@]1(C(=O)COC(=O)C)O)C)O)C)C=NN5C6=CC=CC=C6)C
- subject has role
- anti-inflammatory agent
Sources (2)
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Encyclopedic overview
2 sectionsContents
- References
- External links
Cortivazol is a high-affinity agonist ligand for the glucocorticoid receptor and consequently is classified as a glucocorticoid.
It is sometimes abbreviated "CVZ".
Excerpted from Wikipedia’s “cortivazol” article, available under the CC BY-SA 4.0 licence.
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