deoxycorticosterone

Also known as desoxycortone, 11-deoxycorticosterone, 21-hydroxyprogesterone, 4-pregnen-21-ol-3,20-dione, Reichstein's substance Q, Kendall's desoxy compound B, 21-Hydroxy-3,20-dioxopregn-4-ene, 21-Hydroxy-D4-pregnene-3,20-dione

11-Deoxycorticosterone (DOC), or simply deoxycorticosterone, also known as 21-hydroxyprogesterone, as well as desoxycortone (INN), deoxycortone, and cortexone, is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone. It is an active (Na+-retaining) mineralocorticoid. As its names indicate, can be understood as the 21-hydroxy-variant of progesterone or as the 11-deoxy-variant of corticosterone.

Research

10,114 papers

[Deoxycorticosterone].Nihon rinsho. Japanese journal of clinical medicine · 2005
[Deoxycorticosterone-producing adrenal tumor].Ryoikibetsu shokogun shirizu · 1993
11-Deoxycorticosterone-producing adrenocortical carcinoma.Urologia internationalis · 1998
A case of deoxycorticosterone-producing adrenal adenoma.Endocrine journal · 1995
[11-deoxycorticosterone (DOC) and 18-OH-DOC].Nihon rinsho. Japanese journal of clinical medicine · 1999

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Wikidata facts

Mass: 330.219

Show 4 more facts

chemical formula: C₂₁H₃₀O₃
canonical SMILES: CC12CCC3C(C1CCC2C(=O)CO)CCC4=CC(=O)CCC34C
isomeric SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)CO)CCC4=CC(=O)CC[C@]34C
defined daily dose: 5

Sources (4)

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