Structure via PubChem · Public domain (PubChem)
tazomeline
Sign in to saveTazomeline (LY-287,041) is a drug which acts as a non-selective muscarinic acetylcholine receptor agonist. It was in clinical trials for the treatment of cognitive dysfunction such as that seen in Alzheimer's disease and schizophrenia, but development was apparently scrapped for unknown reasons. Another of the patented uses is for the treatment of "severe painful conditions".
In the Vinony graph
Vinony's link graph records 399 inbound references to tazomeline, and connects out to atropine, muscarinic acetylcholine receptor family and Alzheimer's disease.
It is catalogued under topics including Abandoned drugs, Chemical pages without DrugBank identifier and Drugs not assigned an ATC code.
Vinony links it to 5 Wikipedia language editions.
Chemical data
- Formula
- C14H23N3S2
- Molecular weight
- 297.5 g/mol
- IUPAC name
- 3-hexylsulfanyl-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole
- SMILES
- CCCCCCSC1=NSN=C1C2=CCCN(C2)C
- InChIKey
- XUHMGFKQBWZWPO-UHFFFAOYSA-N
- XLogP
- 3.8
- Polar surface area
- 82.6 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 297.133
Show 3 more facts
- chemical formula
- C₁₄H₂₃N₃S₂
- canonical SMILES
- CCCCCCSC1=NSN=C1C2=CCCN(C2)C
- Commons category
- Tazomeline
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Tazomeline (LY-287,041) is a drug which acts as a non-selective muscarinic acetylcholine receptor agonist. It was in clinical trials for the treatment of cognitive dysfunction such as that seen in Alzheimer's disease and schizophrenia, but development was apparently scrapped for unknown reasons. Another of the patented uses is for the treatment of "severe painful conditions".
== See also == Alvameline Milameline Sabcomeline Xanomeline
Excerpted from Wikipedia’s “tazomeline” article, available under the CC BY-SA 4.0 licence.