Structure via PubChem · Public domain (PubChem)
albaconazole
Sign in to saveAlbaconazole (development code UR-9825) is an experimental triazole antifungal. It has potential broad-spectrum activity. The drug blocks a number of CYP450 liver enzymes.
In the Vinony graph
Within Vinony's link graph, albaconazole is referenced by 95 other articles, and connects out to medication, digital object identifier and infection.
It sits within the topics Chloroarenes, Drugs not assigned an ATC code and Drugs with no legal status.
Its subject is documented across 8 Wikipedia language editions.
Chemical data
- Formula
- C20H16ClF2N5O2
- Molecular weight
- 431.8 g/mol
- IUPAC name
- 7-chloro-3-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]quinazolin-4-one
- SMILES
- C[C@H]([C@](CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3C=NC4=C(C3=O)C=CC(=C4)Cl
- InChIKey
- UHIXWHUVLCAJQL-MPBGBICISA-N
- XLogP
- 2.5
- Polar surface area
- 83.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- vulvovaginitis, tinea pedis, tinea unguium
via ChEMBL · EBI
Research
49 papers- Albaconazole Polymeric Nanocapsules for Treating Trypanosoma cruzi Infections.Pathogens (Basel, Switzerland) · 2025
- Novel triazole antifungal drugs: focus on isavuconazole, ravuconazole and albaconazole.Current opinion in investigational drugs (London, England : 2000) · 2010
- Emerging azole antifungals.Expert opinion on emerging drugs · 2005
- Newer antifungal agents.Expert review of anti-infective therapy · 2011
- Activity of the new triazole derivative albaconazole against Trypanosoma (Schizotrypanum) cruzi in dog hosts.Antimicrobial agents and chemotherapy · 2004
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 431.096
Show 4 more facts
- chemical formula
- C₂₀H₁₆ClF₂N₅O₂
- isomeric SMILES
- C[C@H]([C@](CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3C=NC4=C(C3=O)C=CC(=C4)Cl
- canonical SMILES
- CC(C(CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3C=NC4=C(C3=O)C=CC(=C4)Cl
- subject has role
- antifungal
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Albaconazole (development code UR-9825) is an experimental triazole antifungal. It has potential broad-spectrum activity. The drug blocks a number of CYP450 liver enzymes.
It has also been studied as an antiprotozoal agent.
Excerpted from Wikipedia’s “albaconazole” article, available under the CC BY-SA 4.0 licence.
Available in 8 languages
via Wikidata sitelinks · CC0