albuminuria
Sign in to saveAlbuminuria is a pathological condition of elevated albumin protein in the urine (often measured as urine albumin-to-creatinine ratio of >30 milligrams of albumin per 1 gram of creatinine per day). It is a type of proteinuria, and is the most common protein detected on urinalysis that, when elevated, is associated with kidney and cardiovascular disease (CVD). Albumin is an abundant plasma protein (present in blood) which is normally prevented from being lost into the urine by the sieve-like glomeruli of the nephrons. In healthy people, only trace amounts of it are present in urine, but when th
Key facts
- Medical condition (new).name
- Albuminuria
- Medical condition (new).synonym
- Proteinuria
- Medical condition (new).specialty
- Nephrology
- Medical condition (new).causes
- Diabetes (Type 1 & Type 2), Hypertension, Urinary tract infections, Kidney Disease, Certain Medications
via Wikipedia infobox
Research
26,329 papers- Albuminuria in Cardiovascular, Kidney, and Metabolic Disorders: A State-of-the-Art Review.Circulation · 2025
- Albuminuria: An Underappreciated Risk Factor for Cardiovascular Disease.Journal of the American Heart Association · 2024
- Albuminuria and cardiovascular risk.Hipertension y riesgo vascular · 2023
- Albuminuria and cardiorenal risk.Current opinion in cardiology · 2023
- Change in albuminuria as a surrogate endpoint.Current opinion in nephrology and hypertension · 2019
via PubMed
Clinical Trials
191 registered- COMPLETEDReal Clinical Practice Register of AlbUminuRia Detection in Patients With Previously undiAgnosed Chronic Kidney DiseaseEurasian Association of Therapists · NCT05690009
- COMPLETEDSerum 1,25-dihydroxyvitamin D Levels in Type 2 Diabetes Mellitus Patients With Different Levels of AlbuminuriaTianjin Medical University General Hospital · NCT01845870
- PHASE4COMPLETEDValsartan/Hydrochlorothiazide Combination vs Amlodipine in Patients With Hypertension, Diabetes, and Albuminuria.Novartis · NCT00171561
- COMPLETEDWorld Trade Center Kidney-LinkIcahn School of Medicine at Mount Sinai · NCT03234530
- COMPLETEDDetermining Serum and Urinary Levels of miRNA 192 and miRNA 25 in Patients With and Without Type 2 Diabetes.University of Pisa · NCT04176276
- PHASE2RECRUITINGTargeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, EmpagliflozinUniversity of Illinois at Chicago · NCT07175051
Wikidata facts
Show 2 more facts
- ICPC 2 ID
- U98
- exact match
- purl.obolibrary.org/obo/HP_0012592
Sources (2)
via Wikidata · CC0
~3 min read
Article
5 sectionsContents
- Signs and symptoms
- Causes
- Diagnosis/Testing
- Treatment
- References
Albuminuria is a pathological condition of elevated albumin protein in the urine (often measured as urine albumin-to-creatinine ratio of >30 milligrams of albumin per 1 gram of creatinine per day). It is a type of proteinuria, and is the most common protein detected on urinalysis that, when elevated, is associated with kidney and cardiovascular disease (CVD). Albumin is an abundant plasma protein (present in blood) which is normally prevented from being lost into the urine by the sieve-like glomeruli of the nephrons. In healthy people, only trace amounts of it are present in urine, but when the filtration system of the kidney is damaged, larger amounts of albumin escape into the urine, which can be quantified and used to determine the extent of kidney injury/kidney disease.
==Signs and symptoms== Albuminuria is often asymptomatic in low quantities but foamy urine may be present. As significant albumin is lost to the urine, swelling of the ankles, hands, belly or face may occur (see edema and nephrotic syndrome). This is because a major role of albumin in the blood is to act as an osmotic agent, keeping water from leaving blood vessels and leaking into the surrounding body tissues.