Structure via PubChem · Public domain (PubChem)
algestone
Sign in to saveAlso known as Alphasone
Algestone (), also known as alphasone or alfasone, as well as dihydroxyprogesterone, is a progestin which was never marketed. Another progestin, algestone acetophenide, in contrast, has been marketed as a hormonal contraceptive.
Chemical data
- Formula
- C21H30O4
- Molecular weight
- 346.5 g/mol
- IUPAC name
- (8R,9S,10R,13S,14S,16R,17S)-17-acetyl-16,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
- SMILES
- CC(=O)[C@]1([C@@H](C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O)O
- InChIKey
- CXDWHYOBSJTRJU-SRWWVFQWSA-N
- XLogP
- 2.7
- Polar surface area
- 74.6 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
179 papers- Association of Hormonal Contraceptive Use With Adverse Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials and Cohort Studies.JAMA network open · 2022
- Long-acting injectable contraceptives.Advances in steroid biochemistry and pharmacology · 1976
- Multifocal glioblastoma and hormone replacement therapy in a transgender female.Surgical neurology international · 2023
- Cross-sex hormone therapy in rats induces sex-specific adaptations of renal function and sodium transporters expression.Frontiers in physiology · 2025
- Combination injectable contraceptives for contraception.The Cochrane database of systematic reviews · 2013
via PubMed
Wikidata facts
- Subclass of
- steroid
- Mass
- 346.214
Show 5 more facts
- chemical formula
- C₂₁H₃₀O₄
- isomeric SMILES
- CC(=O)[C@]1([C@@H](C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O)O
- canonical SMILES
- CC(=O)C1(C(CC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)O)O
- World Health Organisation international non-proprietary name
- algestone
- Commons category
- Algestone
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Chemistry
- References
Algestone (), also known as alphasone or alfasone, as well as dihydroxyprogesterone, is a progestin which was never marketed. Another progestin, algestone acetophenide, in contrast, has been marketed as a hormonal contraceptive.
==Chemistry==
Excerpted from Wikipedia’s “algestone” article, available under the CC BY-SA 4.0 licence.
Available in 7 languages
via Wikidata sitelinks · CC0