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alitame

Structure via PubChem · Public domain (PubChem)

EntityQ424676· pop 17· linked from 74 articles

Also known as alitame anhydrous

Alitame is an aspartic acid-containing dipeptide sweetener. It was developed by Pfizer in the early 1980s and currently marketed in some countries under the brand name Aclame. Most dipeptides are not sweet, but the unexpected discovery of aspartame in 1965 led to a search for similar compounds that shared its sweetness.

In the Vinony graph

Within Vinony's link graph, alitame is referenced by 74 other articles, and connects out to United States, Mexico and China.

Vinony files it under Chembox image size set, Chemical articles with multiple CAS registry numbers and Chemical articles with multiple compound IDs.

Its subject is documented across 16 Wikipedia language editions.

Chemical data

Formula
C14H25N3O4S
Molecular weight
331.43 g/mol
IUPAC name
(3S)-3-amino-4-oxo-4-[[(2R)-1-oxo-1-[(2,2,4,4-tetramethylthietan-3-yl)amino]propan-2-yl]amino]butanoic acid
SMILES
C[C@H](C(=O)NC1C(SC1(C)C)(C)C)NC(=O)[C@H](CC(=O)O)N
InChIKey
IVBOUFAWPCPFTQ-SFYZADRCSA-N
XLogP
-2.6
Polar surface area
147 Ų
H-bond donors
4
H-bond acceptors
6
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
331.157
Show 5 more facts
has characteristic
bitterness
chemical formula
C₁₄H₂₅N₃O₄S
canonical SMILES
CC(C(=O)NC1C(SC1(C)C)(C)C)NC(=O)C(CC(=O)O)N
isomeric SMILES
C[C@H](C(=O)NC1C(SC1(C)C)(C)C)NC(=O)[C@H](CC(=O)O)N
Commons category
Alitame
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • References
  • External links

Alitame is an aspartic acid-containing dipeptide sweetener. It was developed by Pfizer in the early 1980s and currently marketed in some countries under the brand name Aclame. Most dipeptides are not sweet, but the unexpected discovery of aspartame in 1965 led to a search for similar compounds that shared its sweetness.

Alitame is about 2000 times sweeter than sucrose (table sugar), about 10 times sweeter than aspartame, and has no aftertaste. Its half-life under hot or acidic conditions is about twice as long as aspartame's, although some other artificial sweeteners, including saccharin and acesulfame potassium, are more stable yet. Unlike aspartame, alitame does not contain phenylalanine, and can therefore be used by people with phenylketonuria.

Excerpted from Wikipedia’s “alitame” article, available under the CC BY-SA 4.0 licence.

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