allele

Also known as allel, allelic gene

An allele is a variant of the sequence of nucleotides at a particular location, or locus, on a DNA molecule.

AI overview

An allele is a specific version of a gene—a variant in the DNA sequence at a particular spot on a chromosome. Alleles matter because different versions of the same gene can produce different traits, which is why people can have different eye colors, blood types, or susceptibility to certain conditions even though they share the same genes.

AI-generated from the Wikipedia summary — may contain errors.

Research

344,155 papers

Estimating allele age.ReviewAnnual review of genomics and human genetics · 2000Slatkin M, Rannala BDOI: 10.1146/annurev.genom.1.1.225
Allele Mining Strategies: Principles and Utilisation for Blast Resistance Genes in Rice (Oryza sativa L.).ReviewCurrent issues in molecular biology · 2015Ashkani S, Yusop MR, Shabanimofrad M et al.
Allele Specific Polymerase Chain Reaction (AS-PCR) Assay to Detect Knockdown and Acetylcholinesterase Mutations in Anopheles superpictus.Turkiye parazitolojii dergisi · 2022Yavaşoğlu Sİ, Şimşek FMDOI: 10.4274/tpd.galenos.2022.20592
A Bayesian method for jointly estimating allele age and selection intensity.ReviewGenetics research · 2008Slatkin MDOI: 10.1017/S0016672307008944
[Allele-specific sequencing].Doklady Akademii nauk · 1995Kalinin VN, Olek K, Schmidt W et al.
The O2 allele: questioning the phenotypic definition of an ABO allele.ReviewImmunohematology · 2008Yazer MH, Olsson ML
Using Droplet Digital PCR to Analyze Allele-Specific RNA Expression.Methods in molecular biology (Clifton, N.J.) · 2018Kamitaki N, Usher CL, McCarroll SADOI: 10.1007/978-1-4939-7778-9_23
Variable fragment length allele-specific polymerase chain reaction (VFLASP), a method for simple and reliable genotyping.Molecular and cellular probes · 2023Tóth T, Csaba Á, Bokor A et al.DOI: 10.1016/j.mcp.2023.101910

via PubMed

Wikidata facts

Image: Alleli.svg

Show 2 more facts

Stack Exchange tag: biology.stackexchange.com/tags/allele
Commons category: Allele

Sources (3)

via Wikidata · CC0

~9 min read

Article

9 sections

Contents

Etymology
Alleles that lead to dominant or recessive phenotypes
Multiple alleles
Genotype frequencies
Allelic dominance in genetic disorders
Epialleles
Idiomorph
See also
References and notes

An allele is a variant of the sequence of nucleotides at a particular location, or locus, on a DNA molecule.

Alleles can differ at a single position through single-nucleotide polymorphisms, but they can also have insertions and deletions of up to several thousand base pairs. Most alleles result in little or no change in the characteristics of an individual organism but sometimes different alleles can result in different observable phenotypic traits such as antibiotic resistance in bacteria, developmental mutations in fruit flies, and genetic diseases in humans.