KEL

Also known as Kell Blood Group, CD238, Kell metallo-endopeptidase (Kell blood group), Kell Blood Group Glycoprotein, Kell blood group, metallo-endopeptidase, Kell Blood Group Antigen, EC 3.4.24, Kell Blood Group, Metalloendopeptidase

antigen system in humans which determines Kell blood type

Gene data

KEL

Name: Kell metallo-endopeptidase (Kell blood group)
Type: protein-coding
Position: 142,941,114–142,962,363 (−)
Aliases: CD238, ECE3, Kell
Ensembl: ENSG00000276615
RefSeq RNA: NM_000420.3, XM_005249993.2, XM_047420357.1, XM_054328705.1, XM_054328706.1
RefSeq protein: NP_000411.1, XP_005250050.1, XP_047276313.1, XP_054184680.1, XP_054184681.1

This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. [provided by RefSeq, Jul 2008].