ambuphylline

Ambuphylline (or bufylline) is a combination of theophylline and aminoisobutanol used as a bronchodilator. It also acts and may be used as a diuretic.

Chemical data

Formula: C11H19N5O3
Molecular weight: 269.3 g/mol
IUPAC name: 2-amino-2-methylpropan-1-ol;1,3-dimethyl-7H-purine-2,6-dione
SMILES: CC(C)(CO)N.CN1C2=C(C(=O)N(C1=O)C)NC=N2
InChIKey: SEIRRUDMPNNSCY-UHFFFAOYSA-N
Polar surface area: 116 Å²
H-bond donors: 3
H-bond acceptors: 5
Formal charge: 0

via PubChem

Drug data · ChEMBL

Molecule type: Small molecule
Indications: Airway obstruction

via ChEMBL · EBI

Research

7 papers

Acute and chronic toxicity studies on theophylline aminoisobutanol and theophylline ethylenediamine.The Journal of laboratory and clinical medicine · 1946
A study of the clinical effects and tolerance of theophylline aminoisobutanol.Proceedings [of the] annual meeting. Central Society for Clinical Research (U.S.) · 1946
DETERMINATION OF IN VIVO AND IN VITRO RELEASE OF THEOPHYLLINE AMINOISOBUTANOL IN A PROLONGED-ACTION SYSTEM.Journal of pharmaceutical sciences · 1965
The effect of theophylline aminoisobutanol in the failing experimental heart.Proceedings [of the] annual meeting. Central Society for Clinical Research (U.S.) · 1945
The effect of theophylline aminoisobutanol in the failing experimental heart.The Journal of laboratory and clinical medicine · 1946

via PubMed

Wikidata facts

Instance of: combination drug
Has part: aminomethylpropanol
Mass: 269.149

Show 3 more facts

chemical formula: C₁₁H₁₉N₅O₃
canonical SMILES: CC(C)(CO)N.CN1C2=C(C(=O)N(C1=O)C)NC=N2
subject has role: bronchodilator

Sources (2)

via Wikidata · CC0

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Encyclopedic overview

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Contents

References

Ambuphylline (or bufylline) is a combination of theophylline and aminoisobutanol used as a bronchodilator. It also acts and may be used as a diuretic.

==References==

Excerpted from Wikipedia’s “ambuphylline” article, available under the CC BY-SA 4.0 licence.

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