doxofylline
Sign in to saveAlso known as Maxivent, ABC 12/3, Doxophylline
Doxofylline (also known as doxophylline) is a phosphodiesterase inhibiting bronchodilator used in the treatment of chronic respiratory diseases such as asthma and COPD. Like theophylline, it is a xanthine derivative.
Key facts
- Drug.PubChem
- 50942
- Drug.UNII
- MPM23GMO7Z
- Drug.KEGG
- D03898
- Drug.ATC_suffix
- DA11
- Drug.verifiedrevid
- 444222727
- Drug.IUPAC_name
- 7-(1,3-Dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione
- Drug.image
- Doxofylline.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 175
- Drug.image2
- Doxofylline-3D-balls.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 225
- Drug.legal_status
- Rx-only
- Drug.routes_of_administration
- By mouth
- Drug.CAS_number
- 69975-86-6
- Drug.ATC_prefix
- R03
- Drug.DrugBank
- DB09273
- Drug.ChemSpiderID
- 46175
via Wikipedia infobox
Wikidata facts
- Mass
- 266.101505
Show 4 more facts
- chemical formula
- C₁₁H₁₄N₄O₄
- World Health Organisation international non-proprietary name
- doxofylline
- canonical SMILES
- CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC3OCCO3
- Commons category
- Doxofylline
Sources (2)
via Wikidata · CC0
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Article
5 sectionsContents
- Medical uses
- Pharmacology
- Names
- References
- Further reading
Doxofylline (also known as doxophylline) is a phosphodiesterase inhibiting bronchodilator used in the treatment of chronic respiratory diseases such as asthma and COPD. Like theophylline, it is a xanthine derivative.
==Medical uses== Doxophylline is used to treat chronic respiratory diseases such as asthma and COPD. in clinical studies, it appears to be equal in efficacy to theophylline but with significantly fewer side effects. In 2014, the US Food and Drug Administration (FDA) granted an orphan drug designation to doxofylline for the treatment of bronchiectasis following the submission of an application by Alitair Pharmaceuticals.
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