Structure via PubChem · Public domain (PubChem)
quazinone
Sign in to saveQuazinone (Dozonone) is a cardiotonic and vasodilator drug which was developed and marketed in the 1980s for the treatment of heart disease. It acts as a selective PDE3 inhibitor. It is no longer available.
Chemical data
- Formula
- C11H10ClN3O
- Molecular weight
- 235.67 g/mol
- IUPAC name
- (3R)-6-chloro-3-methyl-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one
- SMILES
- C[C@@H]1C(=O)N=C2N1CC3=C(N2)C=CC=C3Cl
- InChIKey
- BHZFZYLBVSWUMT-ZCFIWIBFSA-N
- XLogP
- 1.4
- Polar surface area
- 44.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 235.051
Show 4 more facts
- Commons category
- Quazinone
- chemical formula
- C₁₁H₁₀ClN₃O
- isomeric SMILES
- C[C@@H]1C(=O)N=C2N1CC3=C(N2)C=CC=C3Cl
- canonical SMILES
- CC1C(=O)N=C2N1CC3=C(N2)C=CC=C3Cl
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- External links
Quazinone (Dozonone) is a cardiotonic and vasodilator drug which was developed and marketed in the 1980s for the treatment of heart disease. It acts as a selective PDE3 inhibitor. It is no longer available.
== See also == Phosphodiesterase inhibitor
Excerpted from Wikipedia’s “quazinone” article, available under the CC BY-SA 4.0 licence.