Structure via PubChem · Public domain (PubChem)
quazinone
Sign in to saveQuazinone (Dozonone) is a cardiotonic and vasodilator drug which was developed and marketed in the 1980s for the treatment of heart disease. It acts as a selective PDE3 inhibitor. It is no longer available.
In the Vinony graph
Within Vinony's link graph, quazinone is referenced by 95 other articles, and connects out to adrenergic receptor, sympathomimetic drug and Cardiac stimulant.
It sits within the topics Chemical pages without DrugBank identifier, Chloroarenes and Drugs not assigned an ATC code.
Its subject is documented across 5 Wikipedia language editions.
Chemical data
- Formula
- C11H10ClN3O
- Molecular weight
- 235.67 g/mol
- IUPAC name
- (3R)-6-chloro-3-methyl-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one
- SMILES
- C[C@@H]1C(=O)N=C2N1CC3=C(N2)C=CC=C3Cl
- InChIKey
- BHZFZYLBVSWUMT-ZCFIWIBFSA-N
- XLogP
- 1.4
- Polar surface area
- 44.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 235.051
Show 4 more facts
- Commons category
- Quazinone
- chemical formula
- C₁₁H₁₀ClN₃O
- isomeric SMILES
- C[C@@H]1C(=O)N=C2N1CC3=C(N2)C=CC=C3Cl
- canonical SMILES
- CC1C(=O)N=C2N1CC3=C(N2)C=CC=C3Cl
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- External links
Quazinone (Dozonone) is a cardiotonic and vasodilator drug which was developed and marketed in the 1980s for the treatment of heart disease. It acts as a selective PDE3 inhibitor. It is no longer available.
== See also == Phosphodiesterase inhibitor
Excerpted from Wikipedia’s “quazinone” article, available under the CC BY-SA 4.0 licence.