aminophylline
Also known as aminophilline, Somophyllin, Truphylline, Phyllocontin, Peterphyllin, Aminophylline Dye Free, Aminophylline In Sodium Chloride, Somophyllin-Df
Aminophylline is a compound of the bronchodilator theophylline with ethylenediamine in 2:1 ratio. The ethylenediamine improves solubility, and the aminophylline is usually found as a dihydrate.
Chemical data
- Formula
- C16H24N10O4
- Molecular weight
- 420.43 g/mol
- IUPAC name
- bis(1,3-dimethyl-7H-purine-2,6-dione);ethane-1,2-diamine
- SMILES
- CN1C2=C(C(=O)N(C1=O)C)NC=N2.CN1C2=C(C(=O)N(C1=O)C)NC=N2.C(CN)N
- InChIKey
- FQPFAHBPWDRTLU-UHFFFAOYSA-N
- Polar surface area
- 191 Ų
- H-bond donors
- 4
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Research
5,694 papers- Aminophylline in pain and migraine.Pain management · 2023
~4 min read
Article
6 sectionsContents
- Medical uses
- Side effects
- Properties
- Pharmacology
- References
- External links
Aminophylline is a compound of the bronchodilator theophylline with ethylenediamine in 2:1 ratio. The ethylenediamine improves solubility, and the aminophylline is usually found as a dihydrate.
Aminophylline is less potent and shorter-acting than theophylline. Its most common use is in the treatment of airway obstruction from asthma or COPD. Aminophylline is a nonselective adenosine receptor antagonist and phosphodiesterase inhibitor.