Structure via PubChem · Public domain (PubChem)
enprofylline
Sign in to saveAlso known as 3-n-Propylxanthine, 3-Propyl-3,7-dihydro-purine-2,6-dione, 3,7-dihydro-3-Propyl-1H-purine-2,6-dione, 3-Propylxanthine, D-4028, Enprofilina, Enprofyllinum
Enprofylline (3-propylxanthine) is a xanthine derivative used in the treatment of asthma, which acts as a bronchodilator. It acts primarily as a competitive nonselective phosphodiesterase inhibitor with relatively little activity as a nonselective adenosine receptor antagonist.
Chemical data
- Formula
- C8H10N4O2
- Molecular weight
- 194.19 g/mol
- IUPAC name
- 3-propyl-7H-purine-2,6-dione
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
260 papers- Effects of enprofylline and theophylline may show the role of adenosine.Life sciences · 1986
- Theophylline derivatives promote primordial follicle activation via cAMP-PI3K/Akt pathway and ameliorate fertility deficits in naturally aged mice.International journal of biological sciences · 2024
- Enprofylline, a new bronchodilating xanthine derivative.European journal of respiratory diseases · 1983
- Enprofylline in chronic asthma.British journal of diseases of the chest · 1988
- The profile of action of enprofylline, or why adenosine antagonism seems less desirable with xanthine antiasthmatics.Agents and actions. Supplements · 1983
via PubMed
Wikidata facts
- Mass
- 194.08
Show 4 more facts
- chemical formula
- C₈H₁₀N₄O₂
- canonical SMILES
- CCCN1C2=C(C(=O)NC1=O)NC=N2
- World Health Organisation international non-proprietary name
- enprofylline
- Commons category
- Enprofylline
Sources (2)
via Wikidata · CC0
~1 min read
Article
1 sectionsContents
- References
Enprofylline (3-propylxanthine) is a xanthine derivative used in the treatment of asthma, which acts as a bronchodilator. It acts primarily as a competitive nonselective phosphodiesterase inhibitor with relatively little activity as a nonselective adenosine receptor antagonist.
==References==