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ATL-444
Sign in to saveATL-444 is a drug which acts as a potent and reasonably selective antagonist for the adenosine receptors A1 and A2A. It has been used to study the role of the adenosine receptor system in the reinforcing action of cocaine, as well as the development of some cancers.
Chemical data
- Formula
- C17H19N5O
- Molecular weight
- 309.4 g/mol
- IUPAC name
- trans-(1S,3R)-1-[2-(6-amino-9-prop-2-ynylpurin-2-yl)ethynyl]-3-methylcyclohexan-1-ol
- SMILES
- C[C@@H]1CCC[C@](C1)(C#CC2=NC(=C3C(=N2)N(C=N3)CC#C)N)O
- InChIKey
- VEJLEEFUXFQSHP-SJKOYZFVSA-N
- XLogP
- 1.5
- Polar surface area
- 89.9 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 309.15896
Show 4 more facts
- chemical formula
- C₁₇H₁₉N₅O
- canonical SMILES
- CC1CCCC(C1)(C#CC2=NC3=C(C(=N2)N)N=CN3CC#C)O
- isomeric SMILES
- C[C@@H]1CCC[C@](C1)(C#CC2=NC3=C(C(=N2)N)N=CN3CC#C)O
- Commons category
- ATL-444
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
ATL-444 is a drug which acts as a potent and reasonably selective antagonist for the adenosine receptors A1 and A2A. It has been used to study the role of the adenosine receptor system in the reinforcing action of cocaine, as well as the development of some cancers.
== See also == CGS-15943
Excerpted from Wikipedia’s “ATL-444” article, available under the CC BY-SA 4.0 licence.